TGF-HM3R2-100μg / 询价
TGF-HM3R2-500μg / 询价
TGF-HM3R2-500μgx2 / 询价
Human TGF-beta RII/TGFBR2 Protein
Recombinant Human TGF-beta RII/TGFBR2 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at C-Terminus.It contains Ile24-Asp159 [Accession | P37173-1].
The protein has a predicted MW of 44 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC
Less than 1EU per μg by the LAL method.
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
-20 to -80°C for 12 months as supplied from date of receipt.
-80°C for 3 months after reconstitution.
Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TGF-beta RII on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TGF-beta RII is greater than 95% as determined by SEC-HPLC.
Immobilized Human TGF-beta RII, mFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human Mature TGF beta 3, Avi Tag with the EC50 of 6.4ng/ml determined by ELISA (QC Test).
Immobilized Human Mature TGF beta 1, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human TGF-beta RII, mFc Tag with the EC50 of 3.8ng/ml determined by ELISA.
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division.
TGFR2; TGFBR2; TbetaR-II; TGFβR2; TbetaR-II; TGFβR2; AAT3; FAA3; LDS1B; LDS2; LDS2B; MFS2; RIIC; TAAD2; TβR-II; TβR-II
(1)Fricke F, Lee J, Michalak M, et al. TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells. Cell Commun Signal. 2017;15(1):14. Published 2017 Apr 4. doi:10.1186/s12964-017-0169-y.
